(The German Junior Professorship is equivalent to an Assistant Professorship)
Welcome to the group of Matthias Höhne!
Our research focuses on enzyme discovery for biocatalysis.
Our vision is to apply in silico screening approaches for identification of biocatalysts with desired properties (e.g., substrate specificity). Therefore, we study how enzyme function relates with its structure and amino acid sequence.
Additionally, we use protein engineering to improve the protein in the desired way.
Within the ERC Starting grant project LightZymes starting in 2018, we envision to create proteins that use light energy to catalyze novel reactions.
Together with collaborating partners from industry and academia, we apply our identified and engineered catalysts for the synthesis of fine chemicals such as chiral amines.
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