Selected Publications

 

Vianney, Y. M., Jana, J., & Weisz, K. (2024) A pH-responsive topological switch based on a DNA quadruplex-duplex hybrid, Chem. Eur. J., 10.1002/chem.202400722.

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Vianney, Y. M., Dierks, D., & Weisz, K. (2024) Structural differences at quadruplex-duplex interfaces enable ligand-induced topological transitions, Adv. Sci., 2309891,10.1002/advs.202309891.

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Jana, J., Vianney, Y. M., & Weisz, K.* (2024) Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes, Chem. Commun., 10.1039/D3CC05625B.

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Vianney, Y. M., Schröder, N., Jana, J., Chojetzki, G., & Weisz, K.* (2023) Showcasing different G-quadruplex folds of a G-rich sequence: between rule-based prediction and butterfly effect, J. Am. Chem. Soc., 145, 22194-22205. link.

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Vianney, Y. M. & Weisz, K.* (2022) High-affinity binding at quadruplex-duplex junctions: rather the rule than the exception, Nucleic Acids Res., 50, 11948-11964.  link.

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Jana, J., Vianney, Y. M., Schröder, N., & Weisz, K.* (2022) Guiding the folding of G-quadruplexes through loop residue interactions, Nucleic Acids Res., 50, 7161-7175. link
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Vianney, Y. M. & Weisz, K.* (2022) Indoloquinoline ligands favor intercalation at quadruplex-duplex interfaces, Chem. Eur. J., 28, e202103718. link

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Mohr, S., Jana, J., Vianney, Y. M., & Weisz, K.* (2021) Expanding the topological landscape by a G-column flip of a parallel G-quadruplex, Chem. Eur. J., 27, 10437-10447. link
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Vianney, Y. M. & Weisz, K.* (2021) First tandem repeat of a potassium channel KCNN4 minisatellite folds into a V-loop G-quadruplex structure, Biochemistry, 60, 1337-1346. link
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Jana, J. & Weisz, K.* (2021) Thermodynamic stability of G-quadruplexes: impact of sequence and environment, ChemBioChem, 22, 2848-2856. link
__________________________________________________________________________________________________________________________________ Jana, J., Mohr, S., Vianney, Y. M., & Weisz, K.* (2021) Structural motifs and intramolecular interactions in non-canonical G-quadruplexes. RSC Chem. Biol., 2, 338-353. link
__________________________________________________________________________________________________________________________________ Haase, L. & Weisz, K.* (2020) Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design, Nucleic Acids Res., 48, 10555–10566. link
__________________________________________________________________________________________________________________________________     Vianney, Y. M., Preckwinkel, P., Mohr, S. & Weisz, K.* (2020) Quadruplex‐duplex junction: a high‐affinity binding site for indoloquinoline ligands, Chem. Eur. J., 26, 16910-16922. link
__________________________________________________________________________________________________________________________________      Jana, J. & Weisz, K.* (2020) A Thermodynamic Perspective on Potential G‐Quadruplex structures as silencer elements in the MYC promoter, Chem. Eur. J., 26, 17242-17251. link
__________________________________________________________________________________________________________________________________      Haase, L. & Weisz, K.* (2020) Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions, Chem. Commun., 56, 4539-4542. link
__________________________________________________________________________________________________________________________________      Haase, L., Dickerhoff, J. & Weisz, K.* (2020) Sugar puckering drives G-quadruplex refolding: implications for V-shaped loops, Chem. Eur. J., 26, 524-533. link
__________________________________________________________________________________________________________________________________      Funke, A. & Weisz, K.* (2019) Revealing the energetics of ligand-quadruplex interactions using isothermal titration calorimetry. In: Yang, D., Lin, C. (eds) G-Quadruplex Nucleic Acids. Methods in Molecular Biology, vol 2035. Humana, New York, NY link
__________________________________________________________________________________________________________________________________      Karg, B., Mohr, S. & Weisz, K.* (2019) Duplex-guided refolding into novel G-quadruplex (3+1) hybrid conformations, Angew. Chem. Int. Ed., 58, 11068-11071. link
___________________________________________________________________________________________________________________________________     Haase, L., Karg, B. & Weisz, K.* (2019) Manipulating G-quadruplex structures through guanosine analogs, ChemBioChem, 20, 985-993. link

______________________________________________________________________________________________________________________________________     Haase, L., Dickerhoff, J. & Weisz, K.* (2018) DNA-RNA hybrid quadruplexes reveal interactions that favor RNA parallel topologies, Chem. Eur. J., 24, 15365-15371. link
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Funke, A. & Weisz, K.* (2017) Comprehensive thermodynamic profiling for the binding of a G-quadruplex selective indoloquinoline, J. Phys. Chem. B, 121, 5735-5743. link
__________________________________________________________________________________________________________________________________ Dickerhoff, J., Haase, L., Langel, W. & Weisz, K.* (2017) Tracing effects of fluorine substitutions on G-quadruplex conformational changes, ACS Chem. Biol., 12, 1308-1315. link
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Karg, B., Haase, L., Funke, A., Dickerhoff, J. & Weisz, K.* (2016) Observation of a dynamic G-tetrad flip in intramolecular G-quadruplexes, Biochemistry, 55, 6949-6955. link
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Dickerhoff, J., Appel, B., Müller, S. & Weisz, K.* (2016) Sugar-edge interactions in a DNA-RNA G-quadruplex: evidence of sequential C-H∙∙∙O hydrogen bonds contributing to RNA quadruplex folding, Angew. Chem. Int. Ed., 55, 15162-15165. link
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Funke, A., Dickerhoff, J. & Weisz, K.* (2016) Towards the development of structure-selective G-quadruplex-binding indolo[3,2-b]quinolines, Chem. Eur. J., 22, 3170-3181. link
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Dickerhoff, J. & Weisz, K.* (2015) Flipping a G-tetrad in a unimolecular quadruplex without affecting its global fold, Angew. Chem. Int. Ed., 54, 5588-5591. link

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For a full list of publications click here.