Published in Angew. Chem.: An adjusted RBnS protocol and NMR reveal the precise RNA loop preferences of the immuneregulatory protein Roquin

This study, led by the Weigand lab in Marburg, uses a further-developed RNA Bind-n-Seq technology to derive the precise preference of the immunoregulatory protein Roquin for the necessary suppression of transcripts in the immune response from a library of pre-structured RNAs. The findings are supported by high-resolution NMR-based interaction studies in correlation with RNA-protein structure models. The full study can be found in the journal Angewandte Chemie under this link: https://doi.org/10.1002/anie.202412596