In a Perspective article published in Nature Chem. Biology., we discuss the natural diversity of different hydrolase superfamilies suitable to deconstruct polyurethanes (PU) as well as polyamides (Nylons). We examine in detail their catalytic features, strategies for discovering novel biocatalysts and how to tailor them by protein engineering, aiming for a better understanding of these biocatalysts, see here for the full story and here for the press release.
Publication in Nature Chem. Biol.
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