2020 - 2024


M. Smietana, S. Müller. Stimuli-Responsive Boronate Formation to Control Nucleic Acid-Based Functional Architectures, ChemPlusChem, 2024, 89, e202300613,DOI:10.1002/cplu.202300613. link

C.A. Hansen, D. Springstubbe, S. Müller, S. Petkovic. Directed Circularization of a Short RNA. In: Dieterich, C., Baudet, ML. (eds) Circular RNAs. Methods in Molecular Biology, 2024, vol 2765. Humana, New York, NY. link

C. Kaiser, M. Vogel, B. Appel, J. Weigand, S. Müller, B. Suess, J. Wachtveitl. Magnesium Ion-Driven Folding and Conformational Switching Kinetics of Tetracycline Binding Aptamer: Implications for in vivo Riboswitch Engineering. J. Mol. Biol. 2023, 435(20), 168253. link

J. Zhu, R. Hieronymus, S. Müller. A hairpin ribozyme derived spliceozyme. ChemBioChem 2023, e202300204, doi: 10.1002/cbic.202300204. link

A. Hautke, A. Voronin, F. Idiris, A. Riel, F. Lindner, A. Lelièvre-Büttner, J. Zhu, B. Appel, E. Fatti, K. Weis, S. Müller, A. Schug, S. Ebbinghaus. CAG-Repeat RNA Hairpin Folding and Recruitment into Nuclear Speckles with a Pivotal Role of ATP as a Cosolute. J. Am. Chem. Soc. 2023, 145, 9571-9583. link

A. Lelievre-Büttner, T. Schnarr, M. Debiais, M. Smietana, S. Müller. Boronic Acid Assisted Self-Assembly of Functional RNAs. Chem. Eur. J. 202329, e202300196 doi:10.1002/chem.202300196. link

H. Ahrend, B. Appel, L. Jung, S. Müller, M.B. Stope. Reinforcement of the Tumor Suppressing Properties of microRNA-1 by Substitution at the C2’ Position of Varying Ribose Residues in Chemically Synthesized microRNA-1 Molecules. Anticancer Res. 2023, 43(5), 1909-1918. link

S. Müller, J. Frommer: Charge Transfer in Natural and Artificial Nucleic Acids, In: Sugimoto, N. (eds) Handbook of Chemical Biology of Nucleic Acids. Springer, Singapore, 2022, pp 1-20. link

M. Debiais, A.G. Molina, S. Müller, J.-J. Vasseur, I. Barvik, C. Baraguey, M. Smietana. Design and NMR characterization of reversible head-to-tail boronate-linked macrocyclic nucleic acids. Org. Biomol. Chem. 2022, 20, 1889-2895. link

F. Müggenburg, S. Müller. Azide-modified Nucleosides as Versatile Tools for Bioorthogonal Labeling and Functionalization. The chemical record, 2022, e202100322. link

R. Hieronymus, J. Zhu, S. Müller. RNA self-splicing by engineered hairpin ribozyme. Nucleic Acids Res. 2022, 50,

H. Peng, A. Lelievre, K. Landenfeld, S. Müller, I.A. Chen. Vesicle encapsulation stabilizes intermolecular association and structure formation of functional RNA and DNA. Curr. Biol. 2022, 32, 86-96. link

F. Müggenburg, A. Biallas, M. Debiais, M. Smietana, S. Müller. Azido functionalized nucleosides linked to CPG as suitable starting materials for oligonucleotide synthesis by the phosphoramidite approach. Eur. J. Org. Chem., 2021, 6408-6416. link

R. Hieronymus, J. Zhu, B. Appel, S. Müller. Engineering of Hairpin Ribozymes for RNA Processing Reactions. In: Ribozymes: Principles, Methods, Applications. Wiley-VCH, Weinheim, Germany, 2021, 439-461. link

S. Müller, B. Masquida, W. Winkler (eds). Ribozymes: Principles, Methods, Applications. Wiley-VCH, Weinheim, Germany, 2021. link

H. Peng, B. Latifi, S. Müller, A. Lupták, I.A. Chen. Self-cleaving ribozymes: substrate specificity and synthetic biology applications. RSC Chem. Biol. 2021, 2, 1370-1383. link

U.M. Mahajan, Q. Li, A. Alnatsha, J. Maas, M. Orth, S.H. Maier, J. Peterhansl, I. Regel, M. Sendler, P.R. Wagh, N. Mishra, Y. Xue, P. Allawadhi, G. Beyer, J.-P. Kühn, T. Marshall, B. Appel, F. Lämmerhirt, C. Belka, S. Müller, F.-U. Weiss, K. Lauber, M.M. Lerch, J. Mayerle. Tumor-specific delivery of 5FU-incorporated EGFR-targeted aptamers as an efficient treatment in pancreatic ductal adenocarcinoma models. Gastroenterology 2021, 161, 996-1010. link

R. Hieronymus, S. Müller. Towards higher complexity in the RNA world – hairpin ribozyme supported RNA recombination. ChemSystemsChem 2021, 3, e2100003. link

R. Suchsland, B. Appel, P. Virta, S. Müller. Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support. RSC Adv. 2021, 11, 3892-3896. link

M. Debiais, A. Lelievre, J.-J. Vasseur, S. Müller, M. Smietana. Boronic acid-mediated activity control of split 10-23 DNAzymes. Chem. Eur. J. 2021, 27, 1138-1144. link

J. Frommer, S. Müller. Changed reactivity of secondary hydroxyl groups in C8-modified adenosine - lessons learned from silylation. Beilstein J. Org. Chem. 2020, 16, 2854-286. link

J. Frommer, S. Müller. Reductive charge transfer through an RNA aptamer. Angew. Chem. Int. Ed. 2020, 59, 22999-23004. link

M. Debiais, J.-J. Vasseur, S. Müller, M. Smietana. Selective chemical modification of DNA with boronic acids by on-column CuAAc reactions.Synthesis  2020, 52, 2962-2969. link

C. Ebermann, T. Schnarr, S. Müller. Recent advances in understanding circular RNAs. F1000Research  2020, 9, 655. link

D. Balke, R. Hieronymus, S. Müller. Challenges and perspectives in nucleic acid enzyme engineering, Adv. Biochem. Eng. Biotechnol. 2020, 170, 21-35. link

M. Debiais, A. Lelievre, M. Smietana, S. Müller. Splitting Aptamers and Nucleic Acid Enzymes for the Development of Advanced Biosensors. Nucleic Acids Res. 2020, 48, 3400-3422. link

2010 - 2019

R. Suchsland, B. Appel, M. Janczyk, S. Müller, Solid phase assembly of fully protected trinucleotide building blocks for codon based gene synthesis. Appl. Sci. 2019, 9, 2199. link
R. Hieronymus, S. Müller, Engineering of hairpin ribozyme variants for RNA recombination and splicing. Ann. N.Y. Acad. Sci. 2019, 1, 135-143. link
L. Jensen, L. Garrett, S. M. Hölter, B. Rathkolb, I. Rácz, T. Adler, C. Prehn, W. Hans, J. Rozman, L. Becker, J. A. Aguilar-Pimentel, O. Puk, K. Moreth, M. Dopatka, D. J. Walther, V. von Bohlen und Halbach, M. Rath, M. Delatycki, B. Bert, H. Fink, K. Blümlein, M. Ralser, A. Van Dijck, F. Kooy, Z. Stark, S. Müller, H. Scherthan, J. Gecz; W. Wurst, E. Wolf, A. Zimmer, M. Klingenspor, J. Graw, T. Klopstock, D. Busch, J. Adamski, H. Fuchs, V. Gailus-Durner, M. H. de Angelis; O. von Bohlen und Halbach, H. H. Ropers, A.W. Kuß, A mouse model for intellectual disability caused by mutations in the X-linked 2'-O-methyltransferase Ftsj1 gene. Biochim Biophys Acta Mol Basis Dis. 2019, 18, 30497-30506. link
A. Gimenez Molina, I. Barvik, S. Müller, J.-J. Vasseur, M. Smietana. RNA-based boronate internucleosidic linkages: an entry into reversible templated ligation and loop formation. Org Biomol Chem. 2018, 16, 8824-8830. link
R. Suchsland, B. Appel, S. Müller. Synthesis of trinucleotide building blocks in solution and on solid phase. Curr. Protoc. Nucleic Acid Chem. 2018, 75, 1, e60. link
J. Frommer, B. Karg, K. Weisz, S. Müller. Preparation and characterization of pyrene modified uridine derivatives as potential electron donors in RNA. Org. Biomol. Chem. 2018, 16, 7663-7673. link
R. Suchsland, B. Appel, S. Müller. Preparation of trinucleotide phosphoramidites as synthons for gene library synthesis. Beilstein J. Org. Chem. 2018, 14, 397-406. link
S. Petkovic and S. Müller. Synthesis and Engineering of Circular RNAs. Methods Mol. Biol. 2018, 1724, 167-180. link
A. Funke, B. Karg, J. Dickerhoff, D. Balke, S. Müller, K. Weisz. Ligand-Induced Dimerization of a Truncated Parallel MYC G-Quadruplex. ChemBioChem 2018, 19, 505-5012. link
D. Balke, R. Hieronymus, S. Müller. Challenges and perspectives in nucleic acid enzyme engineering. In:Adv. Biochem. Eng. Biotechnol. 2017, link
S. Müller. Phosphorous chemistry in vivo: what makes the phosphoesters in DNA and RNA so diverse? ChemTexts 2017, 3, 9. link
S. Müller and B. Appel. In vitro circularization of RNA. RNA Biol. 2017, 14, 1018-1027. link
S. Müller. Special Issue: Ribozymes and RNA Catalysis. Molecules 2017, 22, 789. link
J. Mueller and S. Müller. Welcome to a SUPA issue. Chem. Biol. Interact. 2016, 259, 1. link
J. Dickerhoff, B. Appel, S. Müller, K. Weisz. Sugar-Edge Interactions in a DNA-RNA G-Quadruplex: Evidence of Sequential C−H∙∙∙O Hydrogen Bonds Contributing to RNA Quadruplex Folding. Angew. Chem. Int. Ed. 2016, 55, 15162-15165. link
S. Müller, B. Appel, D. Balke, R. Hieronymus, C. Nübel. Thirty-five years of research into ribozymes and nucleic acid catalysis: where do we stand today? F1000Res. 2016, 5, 1511. link
D. Balke, A. Becker, S. Müller. In vitro repair of a defective EGFP transcript and translation into a functional protein. Org. Biomol. Chem. 2016, 14, 6729-6737. link
R. Raetz, B. Appel, S. Müller. Preparation of trinucleotide synthons for the synthesis of gene libraries. Chemistry Today 2016, 34, 14-17. link
C. Nübel, B. Appel, I. Hospach, M. Mai, N. Krasteva, G. Nelles, L. Petruschka, S. Müller. Challenges and Opportunities in the Development of Aptamers for TNFα. Appl. Biochem. Biotechnol. 2016179, 398-414. link
R. Hieronymus, S. P. Godehard, D. Balke, S. Müller. Hairpin ribozyme mediated RNA recombination. Chem. Commun. 2016, 52, 4365-4368. link
M. Gao, D. Gnutt, A. Orban, B. Appel, F. Righetti, R. Winter, F. Narberhaus, S. Müller, S. Ebbinghaus. RNA hairpin folding in the crowded cell. Angew. Chem. Int. Ed. 2016, 55, 3224-3228. link
D. Balke, A. Kuss, S. Müller. Landmarks in the evolution of (t)-RNAs from the origin of life up to their present role in human cognition. Life 2016, 6, 1. DOI:10.3390/life6010001 link
S. Müller. Zelluläre Mechanismen des Alterns: DNA-Schäden und Telomerenverkürzung. Sitzungsberichte der Leibniz-Sozietät der Wissenschaften zu Berlin , 2015, 123/124, 245-25. link
S. Petkovic, S. Badelt, S. Block, C. Flamm, M. Delcea, I. Hofacker, S. Müller. Sequence-controlled RNA self-processing: computational design, biochemical analysis and visualization by AFM. RNA 2015, 21, 1249-1260. link
H. Burtscher, S. Berner, R. Seibl, K. Müklegger, S. Müller, K. Weisz. Nucleic Acids. In: Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, Germany, 2015, 1-37. DOI:10.1002/14356007.a18_001.pub2 link
S. Petkovic, S. Müller. RNA circularization strategies in vivo and in vitro. Nucleic Acids Res. 2015, 43, 2454-2465. link
S. Müller. Engineering of ribozymes with useful activities in the ancient RNA world. Ann. N. Y. Acad. Sci. 2015, 1341, 54-60. link
J. Frommer, B. Appel, S. Müller. Ribozymes that can be regulated by external stimuli. Curr. Opin. Biotechnol. 2015, 31, 35-41. link
S. Müller. RNA-Engineering - Rationales Design verschiedener Varianten des Hairpinribozyms. Bioforum 2014, 37, 28-30. link
J. J. Turunen, L. V. Pavlova, M. Hengesbach, M. Helm, S. Müller, R. K. Hartmann, M. J. Frilander. RNA ligation. In:Handbook of RNA Biochemistry (R. K. Hartmann, A. Bindereif, A. Schön, E. Westhof, Eds.), Wiley-VCH, Weinheim, Germany, 2014, 45-88. link
D. Balke, I. Zieten, A. Strahl, O. Müller, S. Müller. Design and characterization of a twin ribozyme for potential repair of a deletion mutation within the oncogenic CTNNB1-ΔS45-mRNA. ChemMedChem 2014, 9, 2128-2137. link
J. Frommer, R. Hieronymus, T. S. Arunachalam, S. Heeren, M. Jenckel, A. Strahl, B. Appel, S. Müller: Preparation of modified long-mer RNAs and analysis of FMN binding to the ypaA aptamer from B. subtilis. RNA Biol. 2014, 11, 609-623. link
N. Rublack and S. Müller. Synthesis of a bifunctional cytidine derivative and its conjugation to RNA for in vitro selection of a cytidine deaminase ribozyme. Beilstein J. Org. Chem. 2014, 10, 1906-1913. link
J. Xu, B. Appel, D. Balke, C. Wichert, S. Müller. RNA aminoacylation mediated by sequential action of two ribozymes and a non-activated amino acid. ChemBioChem 2014, 15, 1200-1209. link
D. Balke, J. Frommer, N. Rublack, D. Springstubbe, B. Appel, S. Müller. Synthesis of site-specifically modified long-mer RNAs. In: Chemical Biology of Nucleic Acids: Fundamentals and Clincial Applications (V. A. Erdmann, W. T. Markiewicz, J. Barciszewski, Eds.), Springer, Berlin Heidelberg, Germany, 2014, 477-496. link
D. Balke, C. Wichert, B. Appel, S. Müller. Generation and selection of ribozyme variants with potential application in protein engineering and synthetic biology. Appl. Microbiol. Biotechnol.2014, 98, 3389-3399. link
S. Petkovic, S. Müller. RNA self-processing: formation of cyclic species and concatemers from a small engineered RNA. FEBS Lett.2013, 587, 2435-2440. link
M. E. Jaax, K. Krauel, T. Marschall, S. Brandt, J. Gansler, B. Fürll, B. Appel, S. Fischer, S. Block, C. A. Helm, S. Müller, K. T. Preissner, A. Greinacher. Complex formation with nucleic acids and aptamers alters antigenic properties of platelet factor 4. Blood 2013, 122, 272-281. link
J. Gansler, M. Jaax, B. Appel, A. Greinacher, K. T. Preissner, S. Fischer. Structural requirements for the procoagulant activity of nucleic acids. PLOS ONE 2012, 11, e50399. DOI:10.1371/journal.pone.0050399 link
S. Müller. Künstliches Leben - Fluch oder Segen der synthetischen Biologie. Sitzungsberichte der Leibniz-Sozietät der Wissenschaften zu Berlin, 2012, 113, 5-14. link
E. A. Khomyakova, E. M. Zubin, L. V. Pavlova, E. V. Kazanova, I. P. Smirnov, G. E. Pozmogova, S. Müller, N. G. Dolinnaya, E. A. Kubareva, R. K. Hartmann, T. S. Oretskaya. 2'-modified Oligoribonucleotides containing 1,2-diol and aldehyde groups. Synthesis and properties. Russ. J. Bioorg. Chem. 2012, 38, 488-499. link
S. Gwiazda, K. Salomon, B. Appel, S. Müller. RNA self-ligation: from oligonucleotides to full length ribozymes. Biochimie 2012, 94, 1457-1463. link
T. S. Arunachalam, C. Wichert, B. Appel, S. Müller. Mixed oligonucleotides for random mutagenesis: best way of making them. Org. Biomol. Chem. 2012, 10, 4641-4650. link
J. Xu, D. Springstubbe, N. Rublack, B. Appel, S. Müller. Synthesis of modified RNA for structure-function studies. Chemistry Today 2012, 30, 42-44. link
B. Appel, T. Marschall, A. Strahl, S. Müller. Kinetic characterization of hairpin ribozyme variants. In: Ribozymes (J. Hartig, Ed.), Wiley-VCH, Weinheim, Germany, 2012, 41-49. link
M. Janczyk, B. Appel, D. Springstubbe, H.-J. Fritz, S. Müller. A new and convenient approach for the preparation of ß-cyanoethyl protected trinucleotide phosphoramidites. Org. Biomol. Chem.2012, 8, 1510-1513. link
S. Müller, B. Appel, T. Krellenberg, S. Petkovic. The many faces of the hairpin ribozyme: structural and functional variants of a small catalytic RNA. IUBMB Life 2012, 64, 36-47. link
I. Drude, A. Strahl, D. Galla, O. Müller, S. Müller. Design of hairpin ribozyme variants with improved activity for poorly processed substrates. FEBS J. 2011, 278, 622-633. link
N. Rublack, D. Springstubbe, H. Nguyen, B. Appel, S. Müller. Synthesis of functionalized RNA: essential tools for the study of RNA structure and ribozyme function. Medimond International Proceedings, Bologna, Italy, 2011, 71-74. link
N. Rublack, H. Nguyen, B. Appel, D. Springstubbe, D. Strohbach, S. Müller. Synthesis of specifically modified oligonucleotides for application in structural and functional analysis of RNA. J. Nucleic Acids2011, article ID 805253, DOI: 10.4061/2011/805253, 1-19. link
S. Sindbert, S. Kalinin, H. Nguyen, A. Kienzler, L. Clima, W. Bannwarth, B. Appel, S. Müller, C. A. M. Seidel. Accurate Distance Determination of Nucleic Acids via Förster Resonance Energy Transfer: implications of Dye Linker Length and Rigidity. J. Am. Chem. Soc. 2011, 133, 2463-2480. link
B. Appel, S. Müller, S. Stingel. Potential of aptamers as receptors in chemical sensors. In: Artifical receptors for chemical sensors (V.M. Miersky, A. K. Yatsimirsky, Eds.), Wiley-VCH, Weinheim, Germany, 2011, 333-355. link
K. Piekielska, M. Gebala, S. Gwiazda, S. Müller, W. Schuhmann. Impedimetric detection of hairpin ribozyme activity. Electroanalysis2011, 23, 37-42. link
D. Wunnicke, D. Strohbach, J. E. Weigand, B. Appel, E. Feresin, B. Suess, S. Müller, H.-J. Steinhoff. Ligand induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR. RNA2011, 17, 182-188. link
S. Müller. Einfachheit biochemischer Komplexität - ein Widerspruch? Sitzungsberichte der Leibnitz-Societät der Wissenschaften zu Berlin, 2010, 108, 57-6. link
J. Sonnemann, C. D. Palani, L. F. Beck, B. Appel. Serine Proteases in Histone Deacetylase Inhibtor-Induced Apoptosis. Still an Unresolved Question. Mol. Cancer Ther. 2010, 9, 2856. link

2000 - 2009

Patent: S. Müller, M. Janczyk. Verfahren zur Herstellung von Trinukleotiden, PCT/EP2010/067313, DE102009046981.8.
Patent: S. Müller, M. Janczyk. Festphasengebundene Nucleoside, PCT/EP2010/067320, DE102009046982.6.
Book: Nucleic Acids from A to Z: A Concise Enyclopedia, Ed. Sabine Müller, Wiley-VCH, Weinheim, Germany, 2008, 336 pp. link
J. Wolf, V. Dombos, B. Appel, S. Müller. Synthesis of guanosine 5'-conjugates and their use as iniator molecules for transcription priming. Org. Biomol.Chem.2008, 6, 899-907. link
D. Strohbach, F. Turcu, W. Schuhmann, S. Müller. Electrochemically induced modulation of the catalytic activity of a reversible redoxsensitive riboswitch. Electroanalysis2008, 20, 935-940. link
I. Drude, S. Vauléon, S. Müller. Twin ribozyme mediated removal of nucleotides from an internal RNA site. Biochem. Biophys. Res. Commun.2007, 363, 24-29. link
I. Drude, V. Dombos, S. Vauléon, S. Müller. Drugs made of RNA: development and application of engineered RNA for gene therapy. Minirev. Med. Chem.2007, 7, 912-931. link
S. Pieper, S. Vauléon, S. Müller. RNA self-processing towards changed topology and sequence oligomerization. Biol.Chem. 2007, 388(7), 743-746. link
S. Müller. Lightening up and down or changing colours. Review of "Methods in Molecular Biology, Vol. 335: Fluorescent Energy Transfer Nucleic Acid Probes: Design and Protocols" by Vladimir V. Didenko, Humana Press Totowa 2006. ChemBioChem2007, 8, 145. link
J. Georg, L. Schomacher, J. P. J. Chong, A. I. Majernik, M. Raabe, H. Urlaub, S. Müller, E. Ciirdaeva, W. Kramer, H.-J. Fritz. The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease. Nucleic Acids Res.2006, 34, 5325-5336. link
A. Kurz, A. Bunge, A.-K. Windeck, M. Rost, W. Flasche, A. Arbuzova, D. Strohbach, S. Müller, J. Liebscher, D. Huster, A. Herrmann. Lipid-anchored oligonucleotides for stable double helix formation in distinct membrane domains. Angew. Chem., 2006, 118, 4550-4554,  Angew. Chem. Int. Ed. 2006, 45, 4440-4444. link
S. Müller, D. Strohbach, J. Wolf. Sensors made of RNA: Tailored ribozymes for detection of small organic molecules, metals, nucleic acids and proteins. IEE Proc. Nanobiotechnol.2006, 153, 31-40. link
D. Strohbach, N. Novak, S. Müller. Redox-active riboswitching: Allosteric regulation of ribozyme activity by ligand shape control. Angew. Chem., 2006, 118, 2181-2184, Angew. Chem. Int. Ed.2006, 45, 2127-2129. link
S. Vauléon, S. A. Ivanov, S. Gwiazda, S. Müller. Site-specific fluorescent and affinity labeling of RNA mediated by an engineered twin ribozyme. ChemBioChem2005, 6, 2158-2162. link
S. A. Ivanov, S. Vauléon, S. Müller. Efficient RNA ligation by reverse-joined hairpin ribozymes and engineering of twin ribozymes consisting of conventional and reverse-joined hairpin ribozyme units. FEBS J.2005, 272, 4464-4474. link
S. Müller. Chemische Biologie, biologische Chemie, bioorganische Chemie, Biochemie Review of "Chemical Biology" by Herbert Waldmann, Petra Janning, Wiley-VCH, Weinheim, 2004. Nachrichten aus der Chemie2005, 53, 51-52. link
S. A. Ivanov, R. Welz, M. A. Gothik, S. Müller. RNA synthesis by T7 RNA polymerase supported primer extension. Mol. Biol., 2004, 38, 798-803. link
S. A. Ivanov, E. M. Volkov, T. S. Oretskaya, S. Müller. Chemical synthesis of an artificially branched hairpin ribozyme variant with RNA cleavage activity. Tetrahedron200460, 9273-9281. link
H.-D. Arndt, R. Welz, S. Müller, B. Ziemer, U. Koert. Stereoselective synthesis of trans-threo-trans oligo-pyrrolidines: potential agents for RNA cleavage. Chem. Eur. J.2004, 10, 3945-3962. link
S. Müller. Ribozymes. In: Highlights in Bioorganic Chemistry (C. Schmuck, H. Wennemers, Eds.), Wiley-VCH, Weinheim, Germany, 2004, 419-421.
S. Müller, R. Welz, S. A. Ivanov, K. Bossmann. Twin Ribozymes. In: Highlights in Bioorganic Chemistry (C. Schmuck, H. Wennemers, Eds.), Wiley-VCH, Weinheim, Germany, 2004, 404-419. link
S. Müller. RNA-Reparatur durch maßgeschneiderte Ribozyme. Bioforum2004, 6, 52-53.
S. Müller, J. Wolf, S. A. Ivanov. Current strategies for the synthesis of RNA. Curr. Org. Synth. 2004, 1, 293-307. link
G. von Kiedrowski, S. Müller. Programmierbare biomolekulare Nanokonstrukte: Molekulare Kopiermaschinen ChemieRubin, Wissenschaftsmagazin der Ruhr-Universität Bochum, Sonderheft , 2003, 12-16.
S. Müller. Engineered ribozymes as molecular tools for site-specific alteration of RNA sequence. ChemBioChem2003, 4, 991-997. link
S. Müller. Another face of RNA: Metabolite induced "Riboswitching" for regulation of gene expression. ChemBioChem2003, 4, 817-819. link
F. V. Subach, S. Müller, V. N. Tashlitsky, O. V. Petrauskene, E. S. Gromova. The preparation of DNA duplexes containing internucleotide phosphorothioate groups in various positions of the recognition site for EcoRII restriction endonuclease. Russ. J. Bioorg. Chem.2003, 29, 566-573. link
R. Welz, K. Bossmann, C. Klug, C. Schmidt, H.-J. Fritz, S. Müller. Site-directed alteration of RNA sequence mediated by an engineered twin ribozyme., Angew. Chem. Int. Ed.2003, 42, 2424-2427. link
S. Vauléon, S. Müller. External regulation of hairpin ribozyme activity by an oligonucleotide effector. ChemBioChem2003, 4, 220-224. link
R. Welz, S. Müller. Polyamine dependent RNA cleavage: Investigations on the function of spermine in hairpin ribozyme catalysis. Collection Symposium Series3 (Z. Tocik and M. Hocek, eds.), Institute of Organic Chemistry and Biochemistry, Academy of Science of the Czech Republic, 2002, Prague, Czech Republic, 251-255.
R. Welz, S. Müller. 5-(Benzylmercapto)-1H-tetrazole as activator for 2'-O-TBDMS phosphoramidite building blocks in RNA synthesis. Tetrahedron Lett.2002, 43, 795-797. link
R. Welz, C. Schmidt, S. Müller. Spermine supports hairpin ribozyme variants to differing extents. Biochem. Biophys. Res. Commmun.2001, 283, 648-654. link
S. Müller. Chemistry then, today and tomorrow. Review of "Chemistry for the 21st Century" by Ehud Keinan, Israel Schechter, WILEY-VCH Weinheim, 2001. Angew. Chem. , 2001, 113, 4223; Angew. Chem. Int. Ed.2001, 40, 4099.
S. Müller. Ribozyme und Twinribozyme: Katalyse ganz anders. Festschrift zu 100 Jahre Chemische Institute in der Hessischen Straße (W. Rettig, B. Kaiser, eds.), Verlag für Marketing und Kommunikation GmbH, 2000, Worms, Germany, 80-85.
R. Welz, C. Schmidt, S. Müller. Rational design and synthesis of ribozymes. Mol. Biol.2000, 34, 934-939. link
O. V. Babkina, A. G. Evstafieva, N. V. Chichkova, A. B. Vartapetian, S. Müller, V. B. Baskunov, O. V. Petrauskene, S. N. Kochetkov, E. S. Gromova. Recombinant components of EcoRII restriction-modification system: Restriction endonuclease can interact with DNA · RNA duplexes. Mol. Biol.2000, 34, 913-920. link
C. Schmidt, R. Welz, S. Müller. RNA double cleavage by a hairpin-derived twin ribozyme. Nucleic Acids Res.2000, 28, 886-894. link

1990 - 1999

S. Müller. Studies on hairpin ribozymes. In: Bioorganic Chemistry, Highlights and New Aspects. (U. Diederichsen, T.K. Lindhorst, B. Westermann and L.A. Wessjohann, Eds.), Wiley-VCH, 1999, Weinheim, Germany, 281-290.
R. Welz, B. Scholz, C. Schmidt, S. Müller: The hairpin ribozyme as a three-way junction" Collection Symposium Series 2 (A. Holy and M. Hocek, eds.) Institute of Organic Chemistry and Biochemistry, Academy of Science of the Czech Republic, 1999, Prague, Czech Republic, 331-334.
B. Scholz, C. Schmidt, R. Welz, S. Müller: Fast quantitative assay of hairpin ribozyme activity based on DNA sequencer technology. Collection Symposium Series 2 (A. Holy and M. Hocek, eds.), Institute of Organic Chemistry and Biochemistry, Academy of Science of the Czech Republic1999, Prague, Czech Republic, 203-208.
C. Schmidt, R. Welz, S. Müller: Ribozyme mediated RNA double cleavage. Collection Symposium Series 2 (A. Holy and M. Hocek, eds.), Institute of Organic Chemistry and Biochemistry, Academy of Science of the Czech Republic, 1999, Prague, Czech Republic, 197-202.
D. J. Earnshaw, B. Masquida, S. Müller, S. Th. Sigurdsson, F. Eckstein, E. Westhof, M. J. Gait. Inter-domain crosslinking and molecular modelling of the hairpin ribozyme. J. Mol. Biol.1997, 274, 197-212. link
S. Schmidt, L. Beigelman, A. Karpeisky, N. Usman, U. S. Sørensen, M. J. Gait. Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: implications for secondary structure. Nucleic Acids Res.1996, 24, 573-581. link
S. Schmidt, D. J. Earnshaw, S. Th. Sigurdsson, F. Eckstein, M. J. Gait. Probing the tertiary structure of the hairpin ribozyme by chemical crosslinking. Collect. Czech. Chem. Commun.1996, 61, 276-279.
S. Schmidt, R. Grenfell, J. Fogg, T. V. Smith, J. A. Grasby, K. Mersmann, M. J. Gait: Solid phase synthesis of oligoribonucleotides containing site-specific modifications". Innovation and Perspectives in Solid Phase Synthesis and Combinatorial Libraries, 4th International Symposium Proceedings1996. (Epton, R., ed.), Mayflower, 1996, Birmingham, UK. 11-18.
S. Schmidt, D. Cech. A new approach to the synthesis of 2-aminopurine-2'-deoxyriboside via Tri-n-butyltin hydride reduction. Nucleosides & Nucleotides1995, 14, 1445-1452. link
O. V. Petrauskene, S. Schmidt, A. S. Karyagina, I. I. Nikolskaya, E. S. Gromova, D. Cech. The interaction of DNA duplexes containing 2-aminopurine with restriction endonucleases EcoRII and SsoII. Nucleic Acids Res. 1995, 23, 2192-2197. link
S. Schmidt, D. Cech. Chemical synthesis of 2'-deoxyoligonucleotides containing 2-aminopurine-2'-deoxyriboside. Collect. Czech. Chem. Commun. 1993, 58, 179-182.
T. Hanck, S. Schmidt, H.-J. Fritz. Sequence-specific and mechanism-based crosslinking of Dcm DNA cytosine-C&sup5;-methyltransferase of E.coli K-12 to synthetic oligonucleotides containing 5-fluoro-2'-deoxycytidine. Nucleic Acids Res. 1993, 21, 303-309. link
W. Gläsner, R. Merkl, S. Schmidt, D. Cech, H.-J. Fritz. Fast quantitative assay of sequence-specific endonuclease activity based on DNA sequencer technology. Biol. Chem. Hoppe-Seyler1992, 373, 1223-1225. link
S. Schmidt, C.-D. Pein, H.-J. Fritz, D. Cech. Chemical synthesis of 2'-deoxyoligonucleotides containing 5-fluoro-2'-deoxycytidine. Nucleic Acids Res. 1992, 20, 2421-2426. link
S. Schmidt, A. Niemann, N. F. Krynetskaya, T. S. Oretskaya, V. G. Metelev, V. V. Suchomlinov, S. A. Shabarova, D. Cech. The use of oligonucleotide probes containing 2'-deoxy-2'-fluoronucleosides for regiospecific cleavage of RNA by RNase H from Escherichia coli. Biochim. Biophys. Acta1992, 1310, 41-46. link
S. Schmidt, L. G. Kusnezowa, E. A. Romanova, A. Niemann, T. S. Oretskaya, V. G. Metelev, S. A. Shabarova: RNA cleavage by hybridase. IV. Oligonucleotide probes with 2'-deoxy-2'-fluoronucleosides and arabinofuranosyl-cytosin. Bioorg. Chem. (Russ.)1991, 17, 823-830.


A. Krug, S. Schmidt, J. Lekschas, K. Lemke, D. Cech. Transformation von Uridin- zu Cytidinderivaten durch selektive Aminierung. Journal f. prakt. Chemie1989, 331, 835-842. link