Professional Experience

Dec. 2001 – Mar. 2024 : Professor for Analytical Biochemistry, Institute of Biochemistry, Universität Greifswald

Oct. 2001 – Nov. 2001: Visiting Professor for Analytical Biochemistry, Institute of Biochemistry, Universität Greifswald

Sept. 1993 – Sept. 2001: Research Associate, Institute of Biology, Chemistry and Pharmacy, Free University of Berlin

March 1990 – July 1993: Postdoctoral Research Associate, Dept. of Pharmaceutical Chemistry, University of California at San Francisco, USA

Mar. 1985 – Feb. 1990: Research Assistant, Dept. of Physical Chemistry, University of Stuttgart

Education

May 2000: Habilitation at the Free University of Berlin, Thesis entitled "NMR studies on the association of nucleobases in free nucleosides and triple helical oligonucleotides" Venia legendi in Physical Chemistry

January 1990: Ph.D., Chemistry, University of Stuttgart, Thesis entitled: "2H NMR Studies on Phospholipid-Cholesterol Interactions in Biological Model Membranes" Advisor: Prof. Dr. G. Kothe

April 1985: Diploma, Chemistry, University of Stuttgart, Thesis entitled: "Proton NMR Studies on Lyotropic Mesophases" Advisor: Prof. Dr. G. Kothe

July 1983: M.Sc., University of Cincinnati, Ohio, USA. Thesis entitled: "Chemical Transformations Involving 1-Hydrazino-Phthalazine" Advisor: Prof. Dr. H. Zimmer

July 1980: Pre-Diploma, Chemistry, University of Stuttgart

Research activities

Being of central importance in biological systems as well as for various medicinal and diagnostic applications, DNA structures and structure-selective nucleic acid ligands constitute primary targets in our studies. Core experimental methodologies of the group include the use of biophysical state-of-the-art instrumentation such as biomolecular NMR spectroscopy, UV-Vis absorption spectroscopy, circular dichroism, fluorescence spectroscopy, and microcalorimetry (ITC, DSC). Lab and computer equipment for synthetic chemistry and molecular modeling work complement available facilities

Publications

PubMed